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产品目录

PD-L1/CD274抗体图片
产品货号:
Z23979
中文名称:
PD-L1/CD274抗体
英文名称:
Anti-PD-L1/CD274 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-PD-L1/CD274 Antibody
指标别名B7 H;B7 H1;B7 homolog 1;B7H1;CD274;CD274 molecule;PD L1;PDCD1 ligand 1;PDCD1L1;PDCD1LG1;PDL1;PD-L1;PD-L1/CD274;Programmed death ligand 1
克隆性Polyclonal
检验物种human
应用范围WB,FCM
基因名称CD274
抗体来源Rabbit
抗体类型IgG
免疫原E.coli-derived human PD-L1 recombinant protein (Position:E45-T290).Human PD-L1 shares 69% amino acid (aa) sequence identity with mouse PD-L1.
实际分子量40~50KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料Programmed death-ligand 1 (PD-L1) also known as CD274 or B7-H1 is a protein that in humans is encoded by the CD274 gene.It is mapped to 9p24.1.PD-L1 is a 40kDa type 1 transmembrane protein that has been speculated to play a major role in suppressing the immune system during particular events such as pregnancy,tissue allografts,autoimmune disease and other disease states such as hepatitis.It has been concluded that upregulation of PD-L1 on tumor MDCs downregulates T-cell immunity and that PD-L1 blockade may represent an approach for cancer immunotherapy.PD-L1 can provide positive costimulatory signals for innate and adaptive immunity and for protection against intracellular bacterial infection.What’s more,It has been found that PD1/PDL1 pathway may be a good target for restoring antitumor immunity in ovarian cancer.
Uniprot IDQ9NZQ7
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称CD274 molecule
蛋白名全称Programmed cell death 1 ligand 1
推荐稀释比
Western blot(WB) 1:500~2000
FCM 1~3μg/1×106 cells

相关搜索:PD-L1/CD274抗体PD-L1抗体CD274多抗Anti-PD-L1/CD274 Antibody
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